Dis`o*be"di*ent (?), a. [Pref. dis- + obedient. See Disobey, Obedient.] 1. Neglecting or refusing to obey; omitting to do what is commanded, or doing what is prohibited; refractory; not observant of duty or rules prescribed by authority; -- applied to persons and acts.

This disobedient spirit in the colonies.

Disobedient unto the word of the Lord.

2. Not yielding.

Medicines used unnecessarily contribute to shorten life, by sooner rendering peculiar parts of the system disobedient to stimuli.